blaCTX-M genes in escherichia coli strains from Croatian Hospitals are located in new (blaCTX-M-3a) and widely spread (blaCTX-M-3a and blaCTX-M-15) genetic structures.

نویسندگان

  • Elzbieta Literacka
  • Branka Bedenic
  • Anna Baraniak
  • Janusz Fiett
  • Marija Tonkic
  • Ines Jajic-Bencic
  • Marek Gniadkowski
چکیده

CTX-M-producing Escherichia coli isolates from three Croatian hospitals were analyzed. All bla(CTX-M-15) genes and one bla(CTX-M-3a) gene resided in widely spread ISEcp1 transposition modules, but other bla(CTX-M-3a) genes were in a new configuration with two IS26 copies, indicating a new event of gene mobilization from a Kluyvera ascorbata genome. The study confirmed the role of the E. coli ST131 clonal group with IncFII-type plasmids in the spread of bla(CTX-M-15) and of IncL/M pCTX-M3-type plasmids in the dissemination of bla(CTX-M-3a).

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 53 4  شماره 

صفحات  -

تاریخ انتشار 2009